MS Nieuw Amsterdam is a Signature class cruise ship for Holland America Line. Nieuw Amsterdam is the 81st ship to enter Holland America's service and the second largest Holland America ship to date.

Holland America Line took the option on building this new sister ship for Eurodam for the 2010 cruising season. She was completed and she sailed on her first set of sea trials on 16 May 2010.

The ship was christened by Princess Maxima of the Netherlands in Venice, Italy on July 4, 2010 before embarking on its maiden voyage from Venice on July 5, 2010.

From April to October the ship visits the Mediterranean and from November to March the ship operates alternating western and eastern itineraries in the Caribbean.

New features on Nieuw Amsterdam include a Pan-Asian restaurant, an African-theme to the Explorer's Lounge, an Italian specialty restaurant and a redesigned atrium and show lounge. Ten cabins have floor-to-ceiling and wall-to-wall windows. Eighty-six percent of the cabins are on the outside, and 67 percent have balconies. It also has dynamic positioning abilities, and is powered by six diesel generators and propelled by Azipod propulsion technology like her older sister Eurodam.